Non-Destructive Real-Time Glucose Quantification Using 5-Turn MeanderedSignal Coplanar Sensor Integrated with Circular PDMS Cavity

In this paper, the experimental demonstration in the prospective application of the novel label-freemicrowave-based Meandered Signal Coplanar Sensor (MSCS), for the non-destructive quantifica-tion of the glucose in aqueous solution, has been presented. The sensor has been designed byembedding 5-turn meander inductor in the signal conductor of a 50  coplanar waveguide (CPW)transmission line, where the sensing area is configured with Polydimethylsiloxane (PDMS). Precur-sory modelling of the CPW transmission line and the meander inductor have been executed inMATLAB and further optimization has been carried out in 3D CST Microwave Studio Suite 2017 sim-ulator. The experimentally measured magnitude and peak frequency for S11 and S21 , respectively,showed good sensitivity of 18.42 dB/g/ml, 265.72 MHz/g/ml, 36.51 dB/g/ml and 1050 MHz/g/ml,respectively. The regression analysis with high linearity of 0.921, 0.944, 0.762, and 0.839, respectively,validated the correlation of the glucose concentration with the magnitude and peak frequency of theS-parameters.